AssocTests: An R Package for Genetic Association Studies

MWASTools: an R/bioconductor package for metabolome-wide association studies

Summary MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statis...

An R package for analysis of whole-genome association studies.

OBJECTIVE To provide data classes and methods to facilitate the analysis of whole genome association studies in the R language for statistical computing. METHODS We have implemented data classes in which each genotype call is stored as a single byte. At this density, data for single chromosomes derived from large studies and new high-throughput gene chip platforms can be handled in memory. We...

SNPassoc: an R package to perform whole genome association studies

UNLABELLED The popularization of large-scale genotyping projects has led to the widespread adoption of genetic association studies as the tool of choice in the search for single nucleotide polymorphisms (SNPs) underlying susceptibility to complex diseases. Although the analysis of individual SNPs is a relatively trivial task, when the number is large and multiple genetic models need to be explo...

An Integrated Genetic Analysis Package Using R

GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studies

GWASTools is an R/Bioconductor package for quality control and analysis of genome-wide association studies (GWAS). GWASTools brings the interactive capability and extensive statistical libraries of R to GWAS. Data are stored in NetCDF format to accommodate extremely large datasets that cannot fit within R's memory limits. The documentation includes instructions for converting data from multiple...